{"kind":"task","effective_mode":"full","benchmark":{"kind":"benchmark","effective_mode":"full","slug":"frontierscience","formal_name":"FrontierScience","introduction":"専門的な科学課題を解く能力を評価するベンチマークです。公開データはolympiadとresearchに分かれ、競技問題と研究課題を区別して扱います。\n\nFrontierScience evaluates the ability to solve expert-level scientific tasks. Its public data separates olympiad and research problems so that competition and research tasks can be examined independently.","introduction_ja":"","introduction_en":"","category":"Category not supplied","task_count":null,"acquisition_status":"Acquisition status not supplied","official_url":"https://huggingface.co/datasets/openai/frontierscience","indexing_mode":"noindex"},"task_id":"a0723d07-6f72-5c50-9467-ee725a800e53","task_key":"olympiad--test--f7b49518~2d6e84~2d44e3~2d9480~2d4cf91d149702","task_revision_id":"1","upstream_id":"f7b49518-6e84-44e3-9480-4cf91d149702","short_description":"In devising a drug delivery system for an in vitro experiment using cultured…","config":"olympiad","split":"test","body":"{\"problem\":\"In devising a drug delivery system for an in vitro experiment using cultured hepatic cells, a PhD student designed three different approaches:\\n\\n- Covalently linking the payload (hereby a small non-bioactive hydrophobic molecule) to a DNA origami structure\\n- Conjugating the payload to a nanobody designed to target a currently unidentified surface orphan receptor.\\n- Linking the payload to a DNA tetrahedron with 20nt-long sides\\n\\nDue to the difficulty of synthesizing DNA nanostructures, the researcher decided to focus on the nanobody approach. After trying to identify the target of the orphan receptors to figure out if it is involved in a phagocytosis-like process, the student's PI told them that the identification does not matter and it would work even if this receptor does not canonically induce endocytosis. What cellular process is the PI depending upon for this novel approach to work?\\n\\nThink step by step and solve the problem below. At the end of your response, write your final answer on a new line starting with “FINAL ANSWER”. It should be an answer to the question such as providing a number, mathematical expression, formula, or entity name, without any extra commentary or providing multiple answer attempts.\",\"subject\":\"biology\"}","display_format":"text","language":"","answer_status":"published","assets":[],"source_url":"https://huggingface.co/datasets/openai/frontierscience","history":"initial import","indexing_mode":"noindex","subproblems":[],"grids":[]}