FrontierScience / 4ee82eb3-a457-42c5-9c62-5730d41f67a6 / A researcher injected a luciferase-encoding plasmid encapsulated in lipid…

Problem

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A researcher injected a luciferase-encoding plasmid encapsulated in lipid nanoparticles intravenously (i.v.) at a dose of 1 mg kg−1 into naive C57BL/6 mice. Within 48 hours, all of the treated mice died. What signaling pathway is most likely to have been responsible?

Think step by step and solve the problem below. At the end of your response, write your final answer on a new line starting with “FINAL ANSWER”. It should be an answer to the question such as providing a number, mathematical expression, formula, or entity name, without any extra commentary or providing multiple answer attempts.

biology

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Source and history

upstream_id / Original problem ID

4ee82eb3-a457-42c5-9c62-5730d41f67a6

task_id

ffb918d0-a565-52c4-898e-b1a9955828e0

task_key

olympiad--test--4ee82eb3~2da457~2d42c5~2d9c62~2d5730d41f67a6

task_revision_id

1

config / split

olympiad / test

Official source

initial import