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MMLU-Pro / 2816 / Tay-Sachs is a disease caused by a recessive allele. Individuals with the…

Problem

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question

Tay-Sachs is a disease caused by a recessive allele. Individuals with the genetic disorder usually do not survive more than a few years, and thus are not able to reproduce and pass on the gene. What would explain how this allele and its associated disease is preserved in the population?

category

biology

options

  1. Occasionally the gene will instead increase the fitness of the individual.
  2. Tay-Sachs is asymptomatic in people who are homozygous recessive.
  3. The recessive allele is actually beneficial in certain environments.
  4. The disease increases the fertility of those who carry it.
  5. Tay-Sachs is a dominant disease, so carriers will show symptoms.
  6. Spontaneous mutation converts the dominant allele to the recessive form.
  7. Heterozygous individuals will show no symptoms.
  8. The gene for Tay-Sachs also provides resistance to another disease.
  9. The disease can be cured, so individuals with the disorder are able to reproduce.
  10. The allele is not preserved and is actually decreasing in frequency.

src

ori_mmlu-high_school_biology

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Source and history

upstream_id / Original problem ID
2816
task_id
26fd71da-ba04-5b93-a5c9-5de10fb92531
task_key
default--test--2816
task_revision_id
1
config / split
default / test

Official source

initial import