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MMLU-Pro / 2918 / Within a few weeks of treatment with the drug 3TC, a patient's HIV population…

Problem

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question

Within a few weeks of treatment with the drug 3TC, a patient's HIV population consists entirely of 3TC-resistant viruses. How can this result best be explained?

category

biology

options

  1. The patient was initially infected with a 3TC-resistant strain of the virus.
  2. The patient's immune system developed a resistance to 3TC, causing the drug to become ineffective.
  3. The 3TC drug triggered a mutation in the HIV virus, causing it to become resistant.
  4. The patient's body started producing 3TC-resistant viruses in response to the drug treatment.
  5. A few drug-resistant viruses were present at the start of treatment, and natural selection increased their frequency.
  6. The HIV virus can naturally resist any form of drug treatment.
  7. The patient must have become reinfected with 3TC-resistant viruses.
  8. HIV began making drug-resistant versions of reverse transcriptase in response to the drug.
  9. The 3TC drug led to an increase in the production of HIV viruses.
  10. HIV can change its surface proteins and resist vaccines.

src

ori_mmlu-high_school_biology

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