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MMLU-Pro / 3228 / The frequency ofTay-Sachs disease in the Jewish population of New York City is…

Problem

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question

The frequency ofTay-Sachs disease in the Jewish population of New York City is about 0.015 and approximately 0.0015 in non-Jewish individuals. Homozygotesdie in infancy or early childhood. If the selection coefficient is 1 and the forward mutation rate is 1 × 10^-6, what is the equilibrium frequency of theTay-Sachs gene in the Jewish population under the combined effects of mutation and selection?

category

biology

options

  1. 0.02
  2. 0.001
  3. 1 × 10^-6
  4. 0.005
  5. 0.00001
  6. 0.1
  7. 0.985
  8. 0.01
  9. 0.0001
  10. 0.015

src

stemez-Genetics

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