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MMLU-Pro / 3284 / The predominant cell type infected by HIV is CD4^+ cells. The mostimportant of…

Problem

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question

The predominant cell type infected by HIV is CD4^+ cells. The mostimportant of these are the T-helper cells. (Review the immunogeneticschapter for a description of T_H-cells.) As the diseaseprogresses through latency into AIDS-related complexand finally full-blown AIDS, the absolute number of CD4^+ cells (i.e., T_H-cells) decreases.The rate of T_H-cell deletionincreases as the patient enters ARC. As the number ofT_H-cells decreases, the ratio of CD4^+ to CD8^+ cells inverts, goingfrom about 2:1 to less than 1:2. Why is the T_H-cell sucha devastating target ?

category

biology

options

  1. T_H-cells are auxiliary cells that enhance the phagocytic function of macrophages without affecting lymphocytes.
  2. T_H-cells are necessary for the proper functioning of the specific immune system, that is, for cytotoxic T-cells (T_c) and most B-cells.
  3. T_H-cells are necessary for the functioning of only B-cells
  4. T_H-cells are primarily involved in the production of mucus as a barrier against pathogens.
  5. T_H-cells are the primary cell type that produces histamine in response to allergens.
  6. T_H-cells are necessary for the maintenance of the skin's barrier function.
  7. T_H-cells are only involved in the initial recognition of pathogens, without influencing the adaptive immune response.
  8. T_H-cells are necessary for the functioning of non-specific immune system
  9. T_H-cells are responsible for the production of antibodies against only non-pathogenic antigens.
  10. T_H-cells are not necessary for the immune system

src

stemez-Genetics

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Source and history

upstream_id / Original problem ID
3284
task_id
2535b4f4-27bf-5386-91e5-7f183a6d48fd
task_key
default--test--3284
task_revision_id
1
config / split
default / test

Official source

initial import