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MMLU-Pro / 6034 / A 23-year-old woman with bone marrow failure is treated with a large dose of…

Problem

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question

A 23-year-old woman with bone marrow failure is treated with a large dose of rabbit antithymocyte globulin. Ten days later, she develops fever, lymphadenopathy, arthralgias, and erythema on her hands and feet. Which of the following is the most likely cause of these symptoms?

category

health

options

  1. Activation of complement system
  2. Overproduction of monocytes
  3. Cytokine secretion by natural killer cells
  4. Hyperactive B-lymphocyte response
  5. Allergic reaction to rabbit proteins
  6. Immune complex deposition in tissues
  7. Polyclonal T-lymphocyte activation
  8. Eosinophil degranulation
  9. Increased production of interferon-gamma
  10. Acute graft-versus-host disease

src

ori_mmlu-professional_medicine

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