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MMLU-Pro / 6047 / A 65-year-old woman presents with progressive muscle weakness that worsens…

Problem

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question

A 65-year-old woman presents with progressive muscle weakness that worsens throughout the day. She reports difficulty climbing stairs, brushing her hair, and speaking for extended periods. Symptoms improve with rest. She has recently experienced double vision and drooping eyelids, especially in the evening. Physical examination shows fatigable weakness of proximal muscles and ptosis. She has no sensory deficits. CT scan of the chest reveals a mass in the anterior mediastinum. Which of the following is the most likely anatomical site of the underlying pathology?

category

health

options

  1. Presynaptic neuromuscular junction
  2. Postsynaptic neuromuscular junction
  3. Motor cortex
  4. Peripheral nerves
  5. Muscle fibers
  6. Spinal cord
  7. Basal ganglia

src

ori_mmlu-professional_medicine

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