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MMLU-Pro / 6245 / A previously healthy 19-year-old college student comes to student health…

Problem

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question

A previously healthy 19-year-old college student comes to student health services 24 hours after the onset of headache, stiff neck, and sensitivity to light. She does not recall any sick contacts. She had chickenpox at the age of 7 years. Her most recent examination 1 year ago included PPD skin testing and showed no abnormalities. She takes a daily multivitamin and an herbal weight-loss preparation. She received all appropriate immunizations during childhood but has not received any since then. She does not smoke, drink alcohol, or use illicit drugs. There is no family history of serious illness. She appears lethargic. Her temperature is 39.1°C (102.4°F), pulse is 112/min, respirations are 20/min, and blood pressure is 100/68 mm Hg. Examination shows diffuse petechiae. Kernig and Brudzinski signs are present. The remainder of the examination shows no abnormalities. A lumbar puncture is performed. Cerebrospinal fluid (CSF) analysis shows numerous segmented neutrophils and a decreased glucose concentration. A Gram stain of the CSF shows gram-negative cocci. Which of the following is the most appropriate pharmacotherapy?

category

health

options

  1. Ceftriaxone
  2. Clindamycin
  3. Erythromycin
  4. Metronidazole

src

ori_mmlu-professional_medicine

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Source and history

upstream_id / Original problem ID
6245
task_id
ae88afb3-9273-5c9f-b0ee-2f57f90ee4d9
task_key
default--test--6245
task_revision_id
1
config / split
default / test

Official source

initial import