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MMLU-Pro / 6311 / A couple comes for preconceptional genetic counseling because they both have a…

Problem

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question

A couple comes for preconceptional genetic counseling because they both have a family history of α-thalassemia. The woman has a minimally decreased hemoglobin concentration. Genetic studies show a single gene deletion. The man has microcytic anemia and a two-gene deletion. If the two-gene deletion is in trans (one deletion on the maternal gene and one deletion on the paternal gene), which of the following percentages of their offspring will have a two-gene deletion?

category

health

options

  1. 75%
  2. 50%
  3. 20%
  4. 80%
  5. 10%
  6. 0%
  7. 66%
  8. 33%
  9. 25%
  10. 100%

src

ori_mmlu-professional_medicine

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