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MMLU / A 5-year-old boy is brought to the physician because of a 2-day history of fever…

Problem

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question

A 5-year-old boy is brought to the physician because of a 2-day history of fever and painful swelling of the left ankle. He has had recurrent cervical lymphadenitis and pneumonia since infancy. Two years ago, a culture from an abscess in the cervical region grew Staphylococcus aureus. His temperature is 38°C (100.4°F). Examination shows a tender, erythematous, edematous left ankle; there is point tenderness over the medial malleolus. A bone scan shows increased uptake in the left lower tibial metaphysis. Culture of bone aspirate grows Serratia marcescens. Nitroblue tetrazolium test shows no color change. Which of the following is the most likely mechanism for these findings?

choices

  1. Developmental arrest of maturation of B lymphocytes
  2. Dysmorphogenesis of the third and fourth pharyngeal pouches
  3. Impaired chemotaxis
  4. Impaired phagocytic oxidative metabolism

subject

professional_medicine

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Source and history

task_id
0fd410ea-7766-51cb-9b67-131998fbbd1f
task_key
all--test--0fd410ea-7766-51cb-9b67-131998fbbd1f
task_revision_id
1
config / split
all / test

Official source

initial import