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MMLU / A 15-year-old girl comes to the physician because of a 3-month history of acne.…

Problem

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question

A 15-year-old girl comes to the physician because of a 3-month history of acne. Breast and pubic hair development began at the age of 12 years. Menarche occurred at the age of 14 years. Physical examination shows scattered open and closed comedones over the cheeks and forehead. Breast and pubic hair development are Tanner stage 5. Which of the following is the most likely underlying cause of this patient's acne?

choices

  1. Increased estrogen stimulation of the sebaceous glands
  2. Increased responsiveness of the sebaceous glands to follicle-stimulating hormone
  3. Increased sympathetic stimulation to the sebaceous glands
  4. Stimulation of the sebaceous glands by androgens

subject

professional_medicine

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